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Article

Uncovering the role of Sgf73 in maintaining SAGA deubiquitinating module structure and activity.

Journal of molecular biology - 24 Apr 2015

Yan Ming, Wolberger Cynthia

Abstract excerpt

The SAGA (Spt-Ada-Gcn5 acetyltransferase) complex performs multiple functions in transcription activation including deubiquitinating histone H2B, which is mediated by a subcomplex called the deubiquitinating module (DUBm). The yeast DUBm comprises a catalytic subunit, Ubp8, and three additional subunits, Sgf11, Sus1 and Sgf73, all of which are required for DUBm activity. A portion of the non-globular Sgf73...

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Identifiers

PMID: 25526805
DOI: 10.1016/j.jmb.2014.12.004
PMCID: PMC4380536

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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