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Article

H2B ubiquitin protease Ubp8 and Sgf11 constitute a discrete functional module within the Saccharomyces cerevisiae SAGA complex.

Molecular and cellular biology - 1 Feb 2005

Ingvarsdottir Kristin, Krogan Nevan J, Emre N C Tolga, Wyce Anastasia, Thompson Natalie J, Emili Andrew, Hughes Timothy R, Greenblatt Jack F, Berger Shelley L

Abstract excerpt

The SAGA complex is a multisubunit protein complex involved in transcriptional regulation in Saccharomyces cerevisiae. SAGA combines proteins involved in interactions with DNA-bound activators and TATA-binding protein (TBP), as well as enzymes for histone acetylation (Gcn5) and histone deubiquitylation (Ubp8). We recently showed that H2B ubiquitylation and Ubp8-mediated deubiquitylation are both required for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15657441
DOI: 10.1128/MCB.25.3.1162-1172.2005
PMCID: PMC544016

Genes

TBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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