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Article

Histological and molecular evaluation of patient-derived colorectal cancer explants.

PloS one - 1 Jan 2012

Uronis Joshua M, Osada Takuya, McCall Shannon, Yang Xiao Yi, Mantyh Christopher, Morse Michael A, Lyerly H Kim, Clary Bryan M, Hsu David S

Abstract excerpt

Mouse models have been developed to investigate colorectal cancer etiology and evaluate new anti-cancer therapies. While genetically engineered and carcinogen-induced mouse models have provided important information with regard to the mechanisms underlying the oncogenic process, tumor xenograft models remain the standard for the evaluation of new chemotherapy and targeted drug treatments for clinical use....

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Identifiers

PMID: 22675560
DOI: 10.1371/journal.pone.0038422
PMCID: PMC3366969

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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