Article
Patients with chronic three-vessel disease in a 15-year follow-up study: genetic and non-genetic predictors of survival.
Medicine - 1 Dec 2014
Máchal Jan, Pávková-Goldbergová Monika, Hlinomaz Ota, Groch Ladislav, Vašků Anna
Abstract excerpt
Genetic and non-genetic predictors of 15-year survival in patients with chronic three-vessel disease (3VD) were investigated. Coronary angiography was performed on 810 subjects with symptoms of stable ischemic heart disease in 1998. The patients with 3VD were genotyped for 23 candidate polymorphisms covering the PPAR-RXR pathway, matrix metalloproteinase-2, renin-angiotensin-aldosterone system, endothelin-1,...
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