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Article

The 5A Allele of the MMP3-Gene Promoter Polymorphism Is a Risk Factor for Poor Outcome of Hemodialysis Patients.

The Tohoku journal of experimental medicine - 1 Aug 2017

Dragovic Jelena Tosic, Popovic Jovan, Djuric Petar, Bulatovic Ana, Jankovic Aleksandar, Buzadzic Ivana, Dimkovic Nada

Abstract excerpt

Cardiovascular morbidity is the leading cause of death in dialysis patients and many risk factors have been involved in its pathogenesis. Genetic susceptibility may be of importance including polymorphism for matrix metalloproteinase 3 (MMP3), which is an enzyme that catalyzes the degradation of collagen, proteoglycans, fibronectin, laminine and elastin. The MMP3 gene promoter contains an insertion/deletion...

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Source

Identifiers

PMID: 28781337
DOI: 10.1620/tjem.242.273

Genes

MMP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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