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Article

POR*28 SNP is associated with lipid response to atorvastatin in children and adolescents with familial hypercholesterolemia.

Pharmacogenomics - 1 Dec 2014

Drogari Euridiki, Ragia Georgia, Mollaki Vasiliki, Elens Laure, Van Schaik Ron H N, Manolopoulos Vangelis G

Abstract excerpt

BACKGROUND: In children and adolescents with familial hypercholesterolemia (FH) pharmacotherapy with statins is the cornerstone in the current regimen to reduce low-density lipoprotein cholesterol (LDLc) and premature coronary heart disease risk. There is, however, a great interindividual variation in response to therapy, partially attributed to genetic factors. The polymorphic enzyme POR transfers electrons from...

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Share to Atorvastatin
Share to Heptanoic Acids

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hyperlipoproteinemia Type II

Share to Lipid Metabolism

Share to Lipoproteins, LDL

Share to NADPH-Ferrihemoprotein Reductase

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Source

Identifiers

PMID: 25521355
DOI: 10.2217/pgs.14.138

Genes

POR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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POR*28 SNP is associated with lipid response to atorvastatin in children and adolescents with familial hypercholesterolemia.PMID 25521355Read ↗

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