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Article

Cell‐based selection provides novel molecular probes for cancer stem cells

14 Nov 2012

Abstract excerpt

Cancer stem cells (CSC) represent a malignant subpopulation of cells in hierarchically organized tumors. They constitute a subpopulation of malignant cells within a tumor mass and possess the ability to self-renew giving rise to heterogeneous tumor cell populations with a complex set of differentiated tumor cells. CSC may be the cause of metastasis and therapeutic refractory disease. Because few markers exist to...

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PMID: 23150432
DOI: 10.1002/ijc.27936

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