Article
Antiretroviral neuropenetration scores better correlate with cognitive performance of HIV-infected patients after accounting for drug susceptibility.
Antiviral therapy - 1 Jan 2015
Fabbiani Massimiliano, Grima Pierfrancesco, Milanini Benedetta, Mondi Annalisa, Baldonero Eleonora, Ciccarelli Nicoletta, Cauda Roberto, Silveri Maria C, De Luca Andrea, Di Giambenedetto Simona
Abstract excerpt
BACKGROUND: The aim of the study was to explore how viral resistance and antiretroviral central nervous system (CNS) penetration could impact on cognitive performance of HIV-infected patients. METHODS: We performed a multicentre cross-sectional study enrolling HIV-infected patients undergoing neuropsychological testing, with a previous genotypic resistance test on plasma samples. CNS penetration-effectiveness...
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