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Article

HIV-associated neurocognitive disorders and central nervous system drug penetration: what next?

Antiviral therapy - 1 Jan 2015

Marra Christina M

Abstract excerpt

The current prevalence of cognitive impairment in HIV-infected individuals is surprisingly high, even in those with undetectable plasma HIV RNA. The aetiology is unknown but one possibility is inadequate control of persistent central nervous system (CNS) HIV infection. The CNS Penetration Effectiveness (CPE) rank has been proposed to predict how well an antiretroviral regimen treats CNS infection. Fabbiani et al....

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Source

Identifiers

PMID: 25781980
DOI: 10.3851/IMP2951

Genes

CPE
GSS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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