Article
The conformation of a catalytic loop is central to GTPase activity on the ribosome.
Biochemistry - 20 Jan 2015
Åqvist Johan, Kamerlin Shina C L
Abstract excerpt
The translational GTPases hydrolyze GTP on the ribosome at several stages of the protein synthesis cycle. Because of the strong conservation of their catalytic center, these enzymes are expected to operate through a universal hydrolysis mechanism, in which a critical histidine residue together wi...
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