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Article

EF-Tu and EF-G are activated by allosteric effects.

Proceedings of the National Academy of Sciences of the United States of America - 27 Mar 2018

Mondal Dibyendu, Warshel Arieh

Abstract excerpt

Many cellular processes are controlled by GTPases, and gaining quantitative understanding of the activation of such processes has been a major challenge. In particular, it is crucial to obtain reliable free-energy surfaces for the relevant reaction paths both in solution and in GTPases active sites. Here, we revisit the energetics of the activation of EF-G and EF-Tu by the ribosome and explore the nature of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29531062
DOI: 10.1073/pnas.1800054115
PMCID: PMC5879710

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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