Article
New insights into the enzymatic role of EF-G in ribosome recycling.
Nucleic acids research - 2 Dec 2015
Zhang Dejiu, Yan Kaige, Zhang Yiwei, Liu Guangqiao, Cao Xintao, Song Guangtao, Xie Qiang, Gao Ning, Qin Yan
Abstract excerpt
During translation, elongation factor G (EF-G) plays a catalytic role in tRNA translocation and a facilitative role in ribosome recycling. By stabilizing the rotated ribosome and interacting with ribosome recycling factor (RRF), EF-G was hypothesized to induce the domain rotations of RRF, which subsequently performs the function of splitting the major intersubunit bridges and thus separates the ribosome into...
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