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Article

Converting structural information into an allosteric-energy-based picture for elongation factor Tu activation by the ribosome.

Proceedings of the National Academy of Sciences of the United States of America - 14 Jun 2011

Adamczyk Andrew J, Warshel Arieh

Abstract excerpt

The crucial process of aminoacyl-tRNA delivery to the ribosome is energized by the GTPase reaction of the elongation factor Tu (EF-Tu). Advances in the elucidation of the structure of the EF-Tu/ribosome complex provide the rare opportunity of gaining a detailed understanding of the activation process of this system. Here, we use quantitative simulation approaches and reproduce the energetics of the GTPase...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21617092
DOI: 10.1073/pnas.1105714108
PMCID: PMC3116401

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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