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Article

The anoctamin family channel subdued mediates thermal nociception in Drosophila.

The Journal of biological chemistry - 23 Jan 2015

Jang Wijeong, Kim Ji Young, Cui Shanyu, Jo Juyeon, Lee Byoung-Cheol, Lee Yeonwoo, Kwon Ki-Sun, Park Chul-Seung, Kim Changsoo

Abstract excerpt

Calcium-permeable and thermosensitive transient receptor potential (TRP) channels mediate the nociceptive transduction of noxious temperature in Drosophila nociceptors. However, the underlying molecular mechanisms are not completely understood. Here we find that Subdued, a calcium-activated chloride channel of the Drosophila anoctamin family, functions in conjunction with the thermo-TRPs in thermal nociception....

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Identifiers

PMID: 25505177
DOI: 10.1074/jbc.M114.592758
PMCID: PMC4303700

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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