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Article

Impact of MIF gene promoter polymorphism on F508del cystic fibrosis patients.

PloS one - 1 Jan 2014

Melotti Paola, Mafficini Andrea, Lebecque Patrick, Ortombina Myriam, Leal Teresinha, Pintani Emily, Pepermans Xavier, Sorio Claudio, Assael Baroukh Maurice

Abstract excerpt

Macrophage migration Inhibitory Factor (MIF) is a pro-inflammatory cytokine sustaining the acute response to gram-negative bacteria and a regulatory role for MIF in Cystic Fibrosis has been suggested by the presence of a functional, polymorphic, four-nucleotide repeat in this gene's promoter at p...

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Share to Cystic Fibrosis
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Forced Expiratory Volume

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Share to Repetitive Sequences, Nucleic Acid

Source

Open in PubMed Open full text

Identifiers

PMID: 25503271
DOI: 10.1371/journal.pone.0114274
PMCID: PMC4264759

Genes

MIF
CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25503271-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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