Article
A genetic role for macrophage migration inhibitory factor (MIF) in adult-onset Still's disease.
Arthritis research & therapy - 1 Jan 2013
Wang Fang-Fang, Huang Xin-Fang, Shen Nan, Leng Lin, Bucala Richard, Chen Shun-Le, Lu Liang-Jing
Abstract excerpt
INTRODUCTION: Adult-onset still's disease (AOSD) is a rare systemic inflammatory disorder in which abnormalities in inflammatory cytokines production appear to play a pathophysiological role. Our previous work has reported increased expression of macrophage migration inhibitory factor (MIF) and revealed its correlation with disease severity and activity in AOSD. A -173 G/C single nucleotide polymorphism (SNP)...
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