Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Complete In Vitro Life Cycle of Trypanosoma congolense: Development of Genetic Tools

2 Mar 2010

Abstract excerpt

BACKGROUND: Animal African trypanosomosis, a disease mainly caused by the protozoan parasite Trypanosoma congolense, is a major constraint to livestock productivity and has a significant impact in the developing countries of Africa. RNA interference (RNAi) has been used to study gene function and identify drug and vaccine targets in a variety of organisms including trypanosomes. However, trypanosome RNAi studies...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Research on Leishmaniasis Studies
Share to Trypanosoma species research and implications
Share to Viral Infectious Diseases and Gene Expression in Insects

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20209144
DOI: 10.1371/journal.pntd.0000618

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Complete In Vitro Life Cycle of Trypanosoma congolense: Development of Genetic ToolsPMID 20209144Read ↗

Reliable, scalable functional genetics in bloodstream-form Trypanosoma congolense in vitro and in vivoSemantic proximity Read ↗

Genetic Engineering of Trypanosoma (Dutonella) vivax and In Vitro Differentiation under Axenic ConditionsSemantic proximity Read ↗

Trypanosoma congolense: In Vitro Culture and TransfectionSemantic proximity Read ↗

High-throughput phenotyping using parallel sequencing of RNA interference targets in the African trypanosome.Semantic proximity Read ↗

Genome-scale RNAi screens for high-throughput phenotyping in bloodstream-form African trypanosomes.Semantic proximity Read ↗

RNA-Seq analysis validates the use of culture-derived Trypanosoma brucei and provides new markers for mammalian and insect life-cycle stagesSemantic proximity Read ↗

Developmental Progression to Infectivity in <i>Trypanosoma brucei</i> Triggered by an RNA-Binding ProteinSemantic proximity Read ↗

Expanding the applications of a bioluminescent mouse infection model of acute African trypanosomiasisSemantic proximity Read ↗

Chromosome-wide analysis of gene function by RNA interference in the african trypanosome.Semantic proximity Read ↗

<em>Trypanosoma cruzi</em> STIB980: A TcI Strain for Drug Discovery and Reverse GeneticsSemantic proximity Read ↗

Identification of positive and negative regulators in the stepwise developmental progression towards infectivity in Trypanosoma bruceiSemantic proximity Read ↗

A limitation lifted: A conditional knockdown system reveals essential roles for Polo-like kinase and Aurora kinase 1 in Trypanosoma cruzi cell divisionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.