Article
A peculiar mutation spectrum emerging from young peruvian patients with hepatocellular carcinoma.
PloS one - 1 Jan 2014
Marchio Agnès, Bertani Stéphane, Rojas Rojas Teresa, Doimi Franco, Terris Benoît, Deharo Eric, Dejean Anne, Ruiz Eloy, Pineau Pascal
Abstract excerpt
Hepatocellular carcinoma usually afflicts individuals in their later years following longstanding liver disease. In Peru, hepatocellular carcinoma exists in a unique clinical presentation, which affects patients around age 25 with a normal, healthy liver. In order to deepen our understanding of the molecular processes ongoing in Peruvian liver tumors, mutation spectrum analysis was carried out on hepatocellular...
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