Article
Frequently mutated genes/pathways and genomic instability as prevention targets in liver cancer.
Carcinogenesis - 1 Jan 2017
Rao Chinthalapally V, Asch Adam S, Yamada Hiroshi Y
Abstract excerpt
The incidence of liver cancer has increased in recent years. Worldwide, liver cancer is common: more than 600000 related deaths are estimated each year. In the USA, about 27170 deaths due to liver cancer are estimated for 2016. Liver cancer is highly resistant to conventional chemotherapy and radiotherapy. For all stages combined, the 5-year survival rate is 15-17%, leaving much to be desired for liver cancer...
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