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Article

The COMT Val/Met polymorphism modulates effects of tDCS on response inhibition.

Brain stimulation - 1 Jan 2000

Nieratschker Vanessa, Kiefer Christoph, Giel Katrin, Krüger Rejko, Plewnia Christian

Abstract excerpt

BACKGROUND: Transcranial direct current stimulation (tDCS) is increasingly discussed as a new option to support the cognitive rehabilitation in neuropsychiatric disorders. However, the therapeutic impact of tDCS is limited by high inter-individual variability. Genetic factors most likely contribu...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25496958
DOI: 10.1016/j.brs.2014.11.009

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25496958-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

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The COMT Val/Met polymorphism modulates effects of tDCS on response inhibition.PMID 25496958Read ↗

Effects of transcranial direct current stimulation (tDCS) on executive functions: influence of COMT Val/Met polymorphism.Semantic proximity Read ↗

Impact of the COMT Val108/158 Met and DAT genotypes on prefrontal function in healthy subjects.Semantic proximity Read ↗

Association of COMT and SLC6A3 polymorphisms with impulsivity, response inhibition and brain function.Semantic proximity Read ↗

COMT Val158Met polymorphism in relation to activation and de-activation in the prefrontal cortex: A study in patients with schizophrenia and healthy subjects.Semantic proximity Read ↗

Both the COMT Val158Met single-nucleotide polymorphism and sex-dependent differences influence response inhibitionSemantic proximity Read ↗

Association of the G1947A COMT (Val(108/158)Met) gene polymorphism with prefrontal P300 during information processing.Semantic proximity Read ↗

Interaction of COMT (Val(108/158)Met) genotype and olanzapine treatment on prefrontal cortical function in patients with schizophrenia.Semantic proximity Read ↗

COMT Val158Met Genotype Determines the Direction of Cognitive Effects Produced by Catechol-O-Methyltransferase InhibitionSemantic proximity Read ↗

Common polymorphisms in dopamine-related genes combine to produce a 'schizophrenia-like' prefrontal hypoactivity.Semantic proximity Read ↗

Influence of SLC6A3 and COMT variation on neural activation during response inhibition.Semantic proximity Read ↗

The effect of the COMT val(158)met polymorphism on neural correlates of semantic verbal fluency.Semantic proximity Read ↗

COMT val158met moderation of dopaminergic drug effects on cognitive function: a critical review.Semantic proximity Read ↗

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