Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Exploring SLC1A5 (ASCT2), SLC7A5, and SLC3A2 (LAT1) Genetic Variants in Colorectal Cancer: Implications for Prognosis and Personalized Care.

Anticancer research - 1 Mar 2026

Lopes Catarina, Macedo-Silva Catarina, Farinha Mónica, Costa João, Pinelas Sofia, Vilas-Boas Isabel, Dinis-Ribeiro Mário, Pereira Carina, Medeiros Rui

Abstract excerpt

BACKGROUND/AIM: Colorectal cancer (CRC) is the second leading cause of cancer-related deaths worldwide, with up to 20% of patients presenting with metastatic disease at diagnosis. The clinical relevance of amino acid transporters ASCT2 and LAT1 in CRC, particularly Caucasian populations, remains underexplored. This study evaluates the prognostic impact of single nucleotide polymorphisms (SNPs) in the genes...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Colorectal Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Kaplan-Meier Estimate

Share to Minor Histocompatibility Antigens

Share to Polymorphism, Single Nucleotide

Share to Precision Medicine

Share to Prognosis

Source

Identifiers

PMID: 41760246
DOI: 10.21873/anticanres.18029

Genes

SLC1A5
SLC3A2
SLC7A5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Exploring SLC1A5 (ASCT2), SLC7A5, and SLC3A2 (LAT1) Genetic Variants in Colorectal Cancer: Implications for Prognosis and Personalized Care.PMID 41760246Read ↗

Protein expression of the amino acid transporter SLC7A5 in tumor tissue is prognostic in early-stage colorectal cancerSemantic proximity Read ↗

An integrated bioinformatic investigation of mitochondrial solute carrier family 25 (SLC25) in colon cancer followed by preliminary validation of member 5 (SLC25A5) in tumorigenesisSemantic proximity Read ↗

Integrative expression quantitative trait locus-based analysis of colorectal cancer identified a functional polymorphism regulating SLC22A5 expression.Semantic proximity Read ↗

A pan-cancer analysis of SLC1A5 in human cancersSemantic proximity Read ↗

Clinical Role of ASCT2 (SLC1A5) in KRAS-Mutated Colorectal Cancer.Semantic proximity Read ↗

Whole exome sequencing identifies novel germline variants of SLC15A4 gene as potentially cancer predisposing in familial colorectal cancer.Semantic proximity Read ↗

Whole Exome Sequencing Identifies Novel Germline Variants of SLC15A4 Gene as Potentially Cancer Predisposing in Familial Colorectal CancerSemantic proximity Read ↗

A comprehensive analysis of SLC25A1 expression and its oncogenic role in pan-cancerSemantic proximity Read ↗

Genetic variations in microRNA-binding sites of solute carrier transporter genes as predictors of clinical outcome in colorectal cancer.Semantic proximity Read ↗

Identification of ABCA5 among ATP-Binding Cassette Transporter Family as a New Biomarker for Colorectal CancerSemantic proximity Read ↗

A comprehensive analysis of SLC25A1 expression and its oncogenic role in pan-cancerSemantic proximity Read ↗

Risk SNP-induced lncRNA-SLCC1 drives colorectal cancer through activating glycolysis signaling.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.