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Article

MicroRNA Binding Site Polymorphisms of the Long-Chain Noncoding RNA MALAT1 are Associated with Risk and Prognosis of Colorectal Cancer in Chinese Han Population.

Genetic testing and molecular biomarkers - 1 May 2020

Yang Qinyan, Zheng Weihong, Shen Zhong, Huang Guoqiang, Yang Guangen

Abstract excerpt

Background: The metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) gene's rs664589 locus is located within the binding site of the miRNA hsa-miR-194-5p for its cognate long-chain noncoding RNA (lncRNA) MALAT1. The aim of this study was to investigate the association between the rs664589 single nucleotide polymorphism (SNP) and the risk and prognosis of colorectal cancer (CRC) in the Chinese Han...

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PMID: 32349546
DOI: 10.1089/gtmb.2020.0013

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