Article
Co-expression of monocarboxylate transporter 1 (MCT1) and its chaperone (CD147) is associated with low survival in patients with gastrointestinal stromal tumors (GISTs).
Journal of bioenergetics and biomembranes - 1 Feb 2012
de Oliveira Antônio Talvane Torres, Pinheiro Céline, Longatto-Filho Adhemar, Brito Maria Jose, Martinho Olga, Matos Delcio, Carvalho André Lopes, Vazquez Vinícius Lima, Silva Thiago Buosi, Scapulatempo Cristovam, Saad Sarhan Sydney, Reis Rui Manuel, Baltazar Fátima
Abstract excerpt
Monocarboxylate transporters (MCTs) have been described to play an important role in cancer, but to date there are no reports on the significance of MCT expression in gastrointestinal stromal tumors (GISTs). The aim of the present work was to assess the value of MCT expression, as well as co-expression with the MCT chaperone CD147 in GISTs and evaluate their clinical-pathological significance. We analyzed the...
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