Article
Gene co-expression network analysis provides novel insights into myostatin regulation at three different mouse developmental timepoints.
PloS one - 1 Jan 2015
Yang Xuerong, Koltes James E, Park Carissa A, Chen Daiwen, Reecy James M
Abstract excerpt
Myostatin (Mstn) knockout mice exhibit large increases in skeletal muscle mass. However, relatively few of the genes that mediate or modify MSTN effects are known. In this study, we performed co-expression network analysis using whole transcriptome microarray data from MSTN-null and wild-type mice to identify genes involved in important biological processes and pathways related to skeletal muscle and adipose...
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