Article
Effect of divalent cation removal on the structure of gram-negative bacterial outer membrane models.
Langmuir : the ACS journal of surfaces and colloids - 1 Jan 2015
Clifton Luke A, Skoda Maximilian W A, Le Brun Anton P, Ciesielski Filip, Kuzmenko Ivan, Holt Stephen A, Lakey Jeremy H
Abstract excerpt
The Gram-negative bacterial outer membrane (GNB-OM) is asymmetric in its lipid composition with a phospholipid-rich inner leaflet and an outer leaflet predominantly composed of lipopolysaccharides (LPS). LPS are polyanionic molecules, with numerous phosphate groups present in the lipid A and core oligosaccharide regions. The repulsive forces due to accumulation of the negative charges are screened and bridged by...
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