Article
Magnesium rescues the morphology of Bacillus subtilis mreB mutants through its inhibitory effect on peptidoglycan hydrolases.
Scientific reports - 21 Jan 2022
Tesson Benoit, Dajkovic Alex, Keary Ruth, Marlière Christian, Dupont-Gillain Christine C, Carballido-López Rut
Abstract excerpt
Cell wall homeostasis in bacteria is tightly regulated by balanced synthesis and degradation of peptidoglycan (PG), allowing cells to expand their sacculus during growth while maintaining physical integrity. In rod-shaped bacteria, actin-like MreB proteins are key players of the PG elongation machinery known as the Rod complex. In the Gram-positive model bacterium Bacillus subtilis depletion of the essential MreB...
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