Article
Crucial roles of charged saccharide moieties in survival of gram negative bacteria against protamine revealed by combination of grazing incidence x-ray structural characterizations and Monte Carlo simulations.
Physical review. E, Statistical, nonlinear, and soft matter physics - 1 Apr 2010
Oliveira Rafael G, Schneck Emanuel, Quinn Bonnie E, Konovalov Oleg V, Brandenburg Klaus, Gutsmann Thomas, Gill Tom, Hanna Charles B, Pink David A, Tanaka Motomu
Abstract excerpt
Grazing incidence x-ray scattering techniques and Monte Carlo (MC) simulations are combined to reveal the influence of molecular structure (genetic mutation) and divalent cations on the survival of gram negative bacteria against cationic peptides such as protamine. The former yields detailed structures of bacterial lipopolysaccharide (LPS) membranes with minimized radiation damages, while the minimal computer...
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