Article
BRCA1 as a nicotinamide adenine dinucleotide (NAD)-dependent metabolic switch in ovarian cancer.
Cell cycle (Georgetown, Tex.) - 1 Jan 2014
Li Da, Chen Na-Na, Cao Ji-Min, Sun Wu-Ping, Zhou Yi-Ming, Li Chun-Yan, Wang Xiu-Xia
Abstract excerpt
Both hereditary factors (e.g., BRCA1) and nicotinamide adenine dinucleotide (NAD)-dependent metabolic pathways are implicated in the initiation and progression of ovarian cancer. However, whether crosstalk exists between BRCA1 and NAD metabolism remains largely unknown. Here, we showed that: (i)...
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