Article
Global analysis of the Bacillus subtilis Fur regulon and the iron starvation stimulon.
Molecular microbiology - 1 Sept 2002
Baichoo Noel, Wang Tao, Ye Rick, Helmann John D
Abstract excerpt
The Bacillus subtilis ferric uptake repressor (Fur) protein coordinates a global transcriptional response to iron starvation. We have used DNA microarrays to define the Fur regulon and the iron starvation stimulon. We identify 20 operons (containing 39 genes) that are derepressed both by mutation of fur and by treatment of cells with the iron chelator 2,2'-dipyridyl. These operons are direct targets of Fur...
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