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Structure-based functional analysis of a PadR transcription factor from Streptococcus pneumoniae and characteristic features in the PadR subfamily-2.

Biochemical and biophysical research communications - 5 Nov 2020

Lee Choongdeok, Kim Meong Il, Park Jaewan, Oh Hansol, Kim Junghun, Hong Jongkwang, Jeon Bo-Young, Ka Hakhyun, Hong Minsun

Abstract excerpt

Since the first discovery of phenolic acid decarboxylase transcriptional regulator (PadR), its homologs have been identified mostly in bacterial species and constitute the PadR family. PadR family members commonly contain a winged helix-turn-helix (wHTH) motif and function as a transcription factor. However, the PadR family members are varied in terms of molecular size and structure. As a result, they are divided...

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Conserved Sequence
Crystallography, X-Ray
Fluorescence Polarization
Multigene Family
Streptococcus pneumoniae

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Structural Homology, Protein

Structure-Activity Relationship

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PMID: 32868077
DOI: 10.1016/j.bbrc.2020.08.035

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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