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Article

First description of the complete human xylosyltransferase-I promoter region.

BMC genetics - 5 Dec 2014

Faust Isabel, Böker Kai Oliver, Lichtenberg Christoph, Kuhn Joachim, Knabbe Cornelius, Hendig Doris

Abstract excerpt

BACKGROUND: Human xylosyltransferase-I (XT-I) catalyzes the rate-limiting step in proteoglycan glycosylation. An increase in XYLT1 mRNA expression and serum XT activity is associated with diseases characterized by abnormal extracellular matrix accumulation like, for instance, fibrosis. Nevertheless, physiological and pathological mechanisms of transcriptional XT regulation remain elusive. RESULTS: To elucidate...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25480529
DOI: 10.1186/s12863-014-0129-0
PMCID: PMC4264549

Genes

XYLT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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