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Article

Human xylosyltransferase I: functional and biochemical characterization of cysteine residues required for enzymic activity.

The Biochemical journal - 1 Mar 2005

Müller Sandra, Schöttler Manuela, Schön Sylvia, Prante Christian, Brinkmann Thomas, Kuhn Joachim, Götting Christian, Kleesiek Knut

Abstract excerpt

XT-I (xylosyltransferase I) is the initial enzyme in the post-translational biosynthesis of glycosaminoglycan chains in proteoglycans. To gain insight into the structure-function relationship of the enzyme, a soluble active form of human XT-I was expressed in High Five insect cells with an apparent molecular mass of 90 kDa. Analysis of the electrophoretic mobility of the protein under non-reducing and reducing...

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Identifiers

PMID: 15461586
DOI: 10.1042/BJ20041206
PMCID: PMC1134786

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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