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Article

Association between MTHFR polymorphisms and congenital heart disease: a meta-analysis based on 9,329 cases and 15,076 controls.

Scientific reports - 4 Dec 2014

Xuan Chao, Li Hui, Zhao Jin-Xia, Wang Hong-Wei, Wang Yi, Ning Chun-Ping, Liu Zhen, Zhang Bei-Bei, He Guo-Wei, Lun Li-Min

Abstract excerpt

The aim of our study was to evaluate the association between polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene and the risk for congenital heart disease (CHD). Electronic literature databases were searched to identify eligible studies published before Jun, 2014. The association was assessed by the odds ratio (OR) with a 95% confidence interval (CI). The publication bias was explored using...

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Source

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Identifiers

PMID: 25472587
DOI: 10.1038/srep07311
PMCID: PMC4255188

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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