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Article

The association between c.1333C > T genetic polymorphism of MTHFR gene and the risk of congenital heart diseases.

Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 Feb 2014

Wang Qiguang, Zhu Xianyang, Lv Bei, Li Xia, Zhang Jing

Abstract excerpt

This study aims to evaluate the influence of methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms on congenital heart diseases (CHD) risk. The frequencies of allelic and genotypic in CHD patients were significantly different from non-CHD controls. Our data suggested that the c.1333C > T genetic polymorphism of MTHFR gene was statistically associated with the increased risk of CHD [TT versus CC: odds...

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Source

Identifiers

PMID: 24387084
DOI: 10.3109/1354750X.2013.876099

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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