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Article

Significance of respirasomes for the assembly/stability of human respiratory chain complex I.

The Journal of biological chemistry - 27 Aug 2004

Schägger Hermann, de Coo René, Bauer Matthias F, Hofmann Sabine, Godinot Catherine, Brandt Ulrich

Abstract excerpt

We showed that the human respiratory chain is organized in supramolecular assemblies of respiratory chain complexes, the respirasomes. The mitochondrial complexes I (NADH dehydrogenase) and III (cytochrome c reductase) form a stable core respirasome to which complex IV (cytochrome c oxidase) can also bind. An analysis of the state of respirasomes in patients with an isolated deficiency of single complexes...

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PMID: 15208329
DOI: 10.1074/jbc.M404033200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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