Article
Genetic variability of respiratory complex abundance, organization and activity in mouse brain.
Genes, brain, and behavior - 1 Feb 2014
Buck K J, Walter N A R, Denmark D L
Abstract excerpt
Mitochondrial dysfunction is implicated in the etiology and pathogenesis of numerous human disorders involving tissues with high energy demand. Murine models are widely used to elucidate genetic determinants of phenotypes relevant to human disease, with recent studies of C57BL/6J (B6), DBA/2J (D2) and B6xD2 populations implicating naturally occurring genetic variation in mitochondrial function/dysfunction. Using...
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