Article
The IL-17A G-197A and IL-17F 7488T/C polymorphisms are associated with increased risk of cancer in Asians: a meta-analysis.
Drug design, development and therapy - 1 Jan 2015
Wang Huifen, Zhang Yanli, Liu Zhaolan, Zhang Yin, Zhao Hongchuan, Du Shiyu
Abstract excerpt
BACKGROUND: Interleukin-17 (IL-17) is a family of emerged pro-inflammatory cytokines. The IL-17A and IL-17F are two important members of IL-17 family. Previous studies have shown that the functional IL-17A G-197A and IL-17F 7488T/C polymorphisms may contribute to susceptibility to cancer but the results were inconclusive. This meta-analysis was performed to determine the exact association between IL-17...
Topics
- Asia
- Asian People
- Gene Frequency
- Genetic Association Studies
- Genetic Predisposition to Disease
- Heterozygote
- Homozygote
- Humans
- Interleukin-17
- Neoplasms
- Odds Ratio
- Phenotype
- Polymorphism, Single Nucleotide
- Risk Assessment