Article
Clinicopathologic correlations of the BRAFV600E mutation, BRAF V600E immunohistochemistry, and BRAF RNA in situ hybridization in papillary thyroid carcinoma.
Pathology, research and practice - 1 Feb 2015
Jung Yoon Yang, Yoo Jae Hyung, Park Eon Sub, Kim Mi Kyung, Lee Tae Jin, Cho Bo Youn, Chung Yun Jae, Kang Kyung Ho, Ahn Hwa Young, Kim Hee Sung
Abstract excerpt
BACKGROUND: The BRAF(V600E) mutation is the most common genetic alteration in papillary thyroid carcinoma (PTC). The aim of this study is to analyze the clinicopathologic correlations of the BRAF(V600E) mutation, BRAF V600E immunohistochemistry (IHC) and BRAF RNA in situ hybridization (ISH) in PTC. METHODS: This study included 467 patients with PTC who underwent surgical resection. We studied the BRAF(V600E)...
Topics
- Adolescent
- Adult
- Aged
- Biomarkers, Tumor
- Carcinoma
- Carcinoma, Papillary
- Female
- Humans
- Immunohistochemistry
- In Situ Hybridization