Article
Expressions of miRNAs in papillary thyroid carcinoma and their associations with the BRAFV600E mutation.
European journal of endocrinology - 1 May 2013
Huang Yongbo, Liao Denghui, Pan Lingxiao, Ye Runyi, Li Xiaoxi, Wang Shenming, Ye Caisheng, Chen Liuhua
Abstract excerpt
OBJECTIVE: Alterations in microRNA (miRNA) expression have been described in thyroid tumors, suggesting a role for miRNAs in thyroid carcinogenesis. BRAF(V600E) is the most frequently identified genetic alteration in papillary thyroid carcinoma (PTC). We investigated the link between BRAF(V600E) status and the expression of miRNAs in PTC and analyzed the associations of these factors with clinicopathological...
Topics
- Adolescent
- Adult
- Aged
- Alleles
- Biomarkers, Tumor
- Carcinoma, Papillary
- Female
- Humans
- Male
- MicroRNAs
- Middle Aged
- Mutation
