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Article

Phenotypic features of patients with schizophrenia carrying de novo gene mutations: a pilot study.

Psychiatry research - 30 Jan 2015

Malherbe P J, Roos J L, Ehlers R, Karayiorgou M, Roos J L

Abstract excerpt

Genome-wide scans have revealed a significant role for de novo copy number variants (CNVs) and Single Nucleotide variants (SNVs) in the genetic architecture of schizophrenia. The present study attempts to parse schizophrenia based on the presence of such de novo mutations and attempts genotype-phenotype correlation. We examined phenotypic variables across three broad categories: clinical presentation, premorbid...

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Source

Identifiers

PMID: 25467704
DOI: 10.1016/j.psychres.2014.10.024

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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