De novo mutation in schizophrenia.

Abstract excerpt

Several studies in the last 5 years have shown that newly arising (de novo) mutations contribute to the genetics of schizophrenia (SZ). This will replenish genetic variants removed by natural selection and could, in part, explain why SZ prevalence has remained stable in the general population despite low fecundity. The strongest evidence to date for the association between SZ and de novo mutation comes from...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to DNA Copy Number Variations
• Share to Genetic Predisposition to Disease
• Share to Mutation