Article
The phenotypic manifestations of rare CNVs in schizophrenia.
Schizophrenia research - 1 Sept 2014
Merikangas Alison K, Segurado Ricardo, Cormican Paul, Heron Elizabeth A, Anney Richard J L, Moore Susan, Kelleher Eric, Hargreaves April, Anderson-Schmidt Heike, Gill Michael, Gallagher Louise, Corvin Aiden
Abstract excerpt
There is compelling evidence for the role of copy number variants (CNVs) in schizophrenia susceptibility, and it has been estimated that up to 2-3% of schizophrenia cases may carry rare CNVs. Despite evidence that these events are associated with an increased risk across categorical neurodevelopmental disorders, there is limited understanding of the impact of CNVs on the core features of disorders like...
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