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Article

Tumoral TP53 and/or CDKN2A alterations are not reliable prognostic biomarkers in patients with localized Ewing sarcoma: a report from the Children's Oncology Group.

Pediatric blood & cancer - 1 May 2015

Lerman Daniel M, Monument Michael J, McIlvaine Elizabeth, Liu Xiao-qiong, Huang Dali, Monovich Laura, Beeler Natalie, Gorlick Richard G, Marina Neyssa M, Womer Richard B, Bridge Julia A, Krailo Mark D, Randall R Lor, Lessnick Stephen L

Abstract excerpt

BACKGROUND: A growing collection of retrospective studies have suggested that TP53 mutations and/or CDKN2A deletions have prognostic significance in Ewing sarcoma. We sought to evaluate these variables in patients with localized disease treated prospectively on a single Children's Oncology Group protocol. PROCEDURE: Of the 568 patients enrolled on Children's Oncology Group protocol AEWS0031 (NCT00006734), 112 had...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25464386
DOI: 10.1002/pbc.25340
PMCID: PMC4376595

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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