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Genetic imbalances revealed by comparative genomic hybridization in Ewing tumors

8 Aug 2001

Abstract excerpt

Ewing tumors are characterized by reciprocal translocations involving the EWS gene on 22q12 fused to ETS transcription-factor family members. Little is known about further aberrations contributing to tumor development and progression. Sixty-two frozen tumors with known EWS rearrangements (52 primary tumors, 10 relapses) of ET patients registered in the EICESS protocol were analyzed by comparative genomic...

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PMID: 11550284
DOI: 10.1002/gcc.1178

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