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Article

Risk stratification by somatic mutation burden in Ewing sarcoma

2 Jan 2019

Abstract excerpt

BACKGROUND: Up to one-third of patients with localized Ewing sarcoma (ES) develop recurrent disease, but current biomarkers do not accurately identify this high-risk group. Therefore, the objective of this study was to determine the utility of mutational burden in predicting outcomes in patients with localized ES. METHODS: Clinical and genomic data from 99 patients with ES, of whom 63 had localized disease at...

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PMID: 30602061
DOI: 10.1002/cncr.31919

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