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Article

Osteoprotegerin Lys3Asn polymorphism and the risk of fracture in older women.

The Journal of clinical endocrinology and metabolism - 1 May 2008

Moffett S P, Oakley J I, Cauley J A, Lui L Y, Ensrud K E, Taylor B C, Hillier T A, Hochberg M C, Li J, Cayabyab S, Lee J M, Peltz G, Cummings S R, Zmuda J M

Abstract excerpt

CONTEXT: Osteoprotegerin (OPG) is a soluble decoy receptor for receptor activator nuclear factor kappa-beta that blocks osteoclastic bone resorption. OBJECTIVE: We investigated the association between a Lys3Asn polymorphism in the OPG gene and bone mineral density (BMD), and the risk of fracture in 6695 women aged 65 yr and older participating in the Study of Osteoporotic Fractures. DESIGN: BMD was measured using...

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Identifiers

PMID: 18319311
DOI: 10.1210/jc.2007-1019
PMCID: PMC2386283

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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