Article
Osteoglycin deficiency does not affect atherosclerosis in mice.
Atherosclerosis - 1 Dec 2014
Moncayo-Arlandi Javier, López-García Alejandro, Fernández M Carmen, Durán Ana Carmen, Fernández Borja
Abstract excerpt
OBJECTIVE: The small leucine-rich proteoglycan Osteoglycin/Mimecan (OGN) is a component of the extracellular matrix, where it regulates collagen fibrillogenesis and cytokine availability. OGN is abundant in normal vessels and in atherosclerotic and restenotic lesions of rat, rabbit and human arteries. Osteoglycin-null mice show alterations in the thickness of collagen fibers of the cornea and the skin. In this...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
