Article
Atheroprotective effects of neuronal nitric oxide synthase in apolipoprotein e knockout mice.
Arteriosclerosis, thrombosis, and vascular biology - 1 Jul 2006
Kuhlencordt Peter J, Hötten Stefanie, Schödel Johannes, Rützel Sebastian, Hu Kai, Widder Julian, Marx Alexander, Huang Paul L, Ertl Georg
Abstract excerpt
OBJECTIVE: All 3 isoforms of the nitric oxide synthase (NOS) are expressed in atherosclerotic lesions. To test whether neuronal NOS (nNOS) deficiency affects atherosclerosis, we studied apoE/nNOSalpha double knockout (DKO) and apolipoprotein E (apoE) knockout (KO) control mice. METHODS AND RESULT...
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