Article
HFE gene and hereditary hemochromatosis: a HuGE review. Human Genome Epidemiology.
American journal of epidemiology - 1 Aug 2001
Hanson E H, Imperatore G, Burke W
Abstract excerpt
Hereditary hemochromatosis (HHC) is an autosomal recessive disorder of iron metabolism characterized by increased iron absorption and deposition in the liver, pancreas, heart, joints, and pituitary gland. Without treatment, death may occur from cirrhosis, primary liver cancer, diabetes, or cardiomyopathy. In 1996, HFE, the gene for HHC, was mapped on the short arm of chromosome 6 (6p21.3). Two of the 37 allelic...
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