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Article

Genetic polymorphisms of innate and adaptive immunity as predictors of outcome in critically ill patients.

Immunobiology - 1 Mar 2015

Kompoti Maria, Michopoulos Alexandros, Michalia Martha, Clouva-Molyvdas Phyllis-Maria, Germenis Anastasios E, Speletas Matthaios

Abstract excerpt

Sepsis and septic shock frequently cause the admission or complicate the clinical course of critically ill patients admitted in the intensive care units (ICU). Genetic variations disrupting the immune sensing of infectious organisms, could affect the ability of the immune system to respond to infection, and may influence both the genetic predisposition to infection and the diversity of the clinical presentation...

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Source

Identifiers

PMID: 25454804
DOI: 10.1016/j.imbio.2014.10.006

Genes

TLR4

Variants

rs9332736
rs4986790
rs9332736
rs4986790

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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